Melatonin is a hormone primarily produced by the pineal gland, and it plays a key role in regulating sleep-wake cycles, also known as the circadian rhythm. Salivary melatonin testing has gained popularity as a non-invasive biomarker due to the ease of sample collection and its close correlation with serum melatonin levels, reflecting the hormone’s biologically active form. Unlike blood tests, saliva collection is simple, cost-effective, and can be done at home, making it ideal for repeated assessments in both research and clinical settings.
In research and clinical contexts, salivary melatonin is commonly used to assess circadian rhythm disorders, sleep disturbances, and conditions related to the pineal gland’s dysfunction. It is particularly useful in studying the effects of shift work, jet lag, and sleep disorders like insomnia and delayed sleep phase syndrome (DSPS). Salivary melatonin measurements also help evaluate the impact of various interventions, such as light exposure therapy or melatonin supplementation, on sleep patterns and circadian alignment. Additionally, salivary melatonin has been employed in research examining the relationship between disrupted sleep cycles and mental health disorders, such as depression and anxiety, providing valuable insights into the physiological mechanisms underlying these conditions.
This product is manufactured in USA by Eagle Biosciences.
Size | 1 x 96 Well |
Sensitivity | 2.1 pg/ml |
Dynamic Range | 1 – 64 pg/mL |
Incubation Time | 2 hours |
Sample Type | Saliva |
Immunogen | |
Source Species | |
Specificity | |
Expression System | |
Clone | |
Group | |
Alpha Chain | |
Beta Chain | |
Peptide | |
Peptide Source | |
Format | |
Buffer | |
Concentration | |
Storage | 2-8°C |
Alternative Names | N-acetyl-5-methoxytryptamine , Sleep Hormone, Endogenous Melatonin, Pineal Hormone, MEL |
Instructions For Use | https://eaglebio.com/wp-content/uploads/2019/03/RUO_MEL32-K01_Melatonin_Serum_ELISA_Package_Insert_V6.pdf |
MSDS | https://eaglebio.com/wp-content/uploads/2019/03/MEL32-K01-Melatonin-Saliva-ELISA-Assay-MSDS.pdf |