Insulin Ultrasensitive ELISA Kit

The Insulin Ultrasensitive ELISA is an advanced immunoassay designed to quantitatively measure insulin levels with exceptional sensitivity and specificity, even at very low concentrations. It employs a sandwich enzyme-linked immunosorbent assay (ELISA) principle, using high-affinity antibodies that specifically bind to human insulin without significant cross-reactivity to proinsulin or C-peptide. This enhanced sensitivity allows for precise detection of basal insulin concentrations in fasting individuals or in samples where insulin levels are near the physiological lower limit, such as in healthy subjects, insulin-resistant states, or post-hypoglycemic conditions.
In research settings, the Insulin Ultrasensitive ELISA is widely used to study insulin dynamics, insulin resistance, and beta-cell function. It supports investigations into metabolic disorders such as diabetes mellitus, obesity, and metabolic syndrome, enabling accurate assessment of fasting insulin, glucose-insulin homeostasis (e.g., HOMA-IR), and pharmacological responses to insulin-sensitizing agents. Its high sensitivity is particularly useful in preclinical and clinical studies exploring early metabolic changes or evaluating interventions aimed at improving insulin sensitivity.
In clinical applications, the assay can assist in evaluating insulin secretion and clearance in patients with suspected dysglycemia, hypoglycemia, or insulinoma. It aids clinicians in distinguishing between endogenous hyperinsulinemia and exogenous insulin administration and in monitoring therapeutic efficacy in diabetes management. Overall, the Insulin Ultrasensitive ELISA provides a robust, reproducible, and sensitive method for insulin quantification, bridging translational research and clinical diagnostics.

This product is manufactured in USA by Eagle Biosciences.