Human [Leu27]IGF-II

Human [Leu27]IGF-II

$190.00

Human [Leu27] insulin-like growth factor-II ([Leu27] IGF-II) is an analogue of human IGF-II with a leucine substitution at position 27. It binds normally to acid-stripped human serum binding proteins but shows a 10–20 fold reduction in type 1 IGF receptor binding. Useful for studying IGF-II activity through non-type 1 receptor pathways. This product is for research use only and not to be used in diagnostic procedures.

SKU: TU100 Category: Tags: , ,

Human [Leu27] insulin-like Growth Factor-II ([Leu27] IGF-II) is an analogue of human IGF-II which has a Leucine substitution in place of Tyrosine at position 27 of the human IGF-II sequence. [Leu27]IGF-II has normal binding to acid-stripped human serum binding proteins but has a 10-20 fold reduction in binding to the type 1 IGF receptor compared to IGF-II. It is a useful analogue for studying the effects of IGF-II through non-type 1 receptor binding mechanisms.

This product is manufactured in Australia by GroPep Bioreagents.

Size 100 µg
Source Species Recombinant
Expression System Ecoli
Storage 2-8°C

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