Human IgD ELISA Kit
Immunoglobulin D (IgD) is one of the five major classes of antibodies and is primarily expressed on the surface of immature B cells, where it plays a role in initiating B cell activation and regulating immune responses. Although present in relatively low concentrations in serum compared to IgG or IgM, IgD contributes to mucosal immunity and the defense against respiratory pathogens. Its functions include facilitating B cell receptor signaling, promoting antibody diversification, and participating in immune surveillance. Dysregulation of IgD levels has been associated with certain autoimmune disorders, infections, and rare hematological malignancies, making it a biomarker of interest in both immunology research and clinical diagnostics.
The IgD ELISA (enzyme-linked immunosorbent assay) provides a sensitive method for quantifying IgD concentrations in serum, plasma, or other biological samples. In research, IgD ELISAs are used to study B cell development, antibody class switching, and mucosal immune responses. They also help investigators examine the role of IgD in autoimmune diseases, chronic infections, and allergic conditions, providing insights into immune system regulation and dysfunction.
Clinically, IgD ELISA can assist in diagnosing immunodeficiencies, monitoring abnormal B cell activity, and detecting rare conditions such as IgD myeloma. It may also serve as a supplementary tool for evaluating immune responses in patients with recurrent infections or autoimmune disorders. By tracking IgD levels, clinicians can gain valuable information on humoral immunity and the status of the patient’s immune system, aiding in both diagnosis and therapeutic decision-making.
This Human IgD ELISA Kit is manufactured in USA by Eagle Biosciences.
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