A sensitive histamine test is an assay designed to accurately detect low levels of histamine in biological samples such as plasma, serum, urine, or tissue. Histamine is a biogenic amine released primarily by mast cells and basophils in response to allergens, tissue injury, or certain drugs, and it plays a central role in immune responses, inflammation, gastric acid secretion, and neurotransmission. Sensitive detection methods, such as high-performance liquid chromatography (HPLC), enzyme-linked immunosorbent assays (ELISA), or mass spectrometry, allow for precise measurement of histamine even at minimal concentrations, making the test valuable for both research and clinical applications.
In research, sensitive histamine tests are used to study allergic reactions, inflammatory processes, mast cell biology, and histamine-mediated neurotransmission. They allow researchers to monitor subtle changes in histamine release, evaluate the effects of pharmacological interventions (such as antihistamines or mast cell stabilizers), and investigate the mechanisms underlying immune activation or neuroimmune interactions. The high sensitivity of these assays is especially important in experimental models where histamine levels may be low but biologically significant.
This product is manufactured in Germany by LDN.
| Size | 1 x 96 Well |
| Sensitivity | 0.2 ng/mL |
| Dynamic Range | 0.5 – 50 ng/mL |
| Incubation Time | Overnight |
| Sample Type | Biological Samples |
| Storage | 2-8°C |
| Alternative Names | 2-(1H-imidazol-4-yl)ethanamine, β-imidazolylethylamine, or histidin-β-ethylamine. |
