easYmers® are peptide-receptive HLA class I molecules designed to generate custom peptide-HLA (pHLA) monomers. Simply add your peptide of interest to create specific monomers, which can then be tetramerized using fluorophore-conjugated streptavidin for T cell staining and analysis by flow cytometry. easYmer® reagents maintain native HLA-I structure without artificial disulfide bonds and are validated using a FACS-based bead assay.
This technology supports:
-Efficient production of pHLA monomers with a single epitope for high-throughput screening,
-Parallel screening of multiple peptide epitope candidates,
-Evaluation and validation of peptide-HLA-I interactions.
This product is manufactured in Denmark by ImmunAware, Inc..
| Size | 50 Test (20 µg of pMHC) |
| Sensitivity | |
| Dynamic Range | |
| Incubation Time | |
| Sample Type | |
| Immunogen | |
| Source Species | |
| Specificity | |
| Expression System | |
| Clone | |
| Group | HLA-B |
| Alpha Chain | HLA-B3508 |
| Beta Chain | b2m |
| Peptide | HAVPFGLVSM |
| Peptide Source | YFV NS2A4–13 |
| Format | easYmer |
| Buffer | TRIS/MALEATE pH 7 |
| Concentration | 3000 nM |
| Storage | -20°C |
| Alternative Names | |
| Instructions For Use | https://eaglebio.com/wp-content/uploads/2025/07/HLA-easYmers®-Full-protocol-1.pdf |
| MSDS | https://eaglebio.com/wp-content/uploads/2025/07/Assessment-of-HLA-complex-folding-FACS-assay.pdf |