Serum Amyloid A (SAA) is an acute-phase protein predominantly synthesized in the liver in response to inflammatory stimuli. In chickens, as in other species, SAA plays a key role in the innate immune response, acting as a sensitive biomarker for inflammation, infection, and tissue damage. Its expression is markedly upregulated during acute-phase responses, often within hours of an inflammatory trigger, making it an effective early indicator of disease. Chicken SAA, like its mammalian counterparts, binds to high-density lipoproteins (HDL) and is involved in modulating immune cell activity, including chemotaxis and cytokine induction.
In research settings, chicken SAA is widely used to monitor health status, evaluate the efficacy of vaccines, and assess responses to pathogenic challenges in experimental models. Its high sensitivity and dynamic range make it suitable for detecting subclinical infections or immune activation in poultry. Clinically, SAA measurement in chickens is valuable for early diagnosis and prognosis of bacterial and viral infections, as well as for monitoring recovery and treatment outcomes. It is often used alongside other acute-phase proteins or clinical signs to improve diagnostic accuracy in veterinary practice and flock management.
This product is manufactured in USA by Eagle Biosciences.