Canine (Dog) Transferrin ELISA Kit

Transferrin is a glycoprotein responsible for iron binding and transport in the bloodstream, playing a crucial role in iron homeostasis and metabolism. In dogs, canine transferrin functions similarly to its counterparts in other mammals, binding ferric ions (Fe³⁺) and delivering them to cells through receptor-mediated endocytosis. It is primarily synthesized in the liver and circulates in the plasma as part of the iron-regulating system. Beyond its role in iron metabolism, transferrin is also considered a negative acute-phase protein, meaning its levels can decrease in response to inflammation, infection, or trauma, making it a potentially valuable biomarker for assessing systemic health status in dogs.

In research settings, canine transferrin has been utilized as a biochemical and molecular marker for studies on iron metabolism, nutritional status, and genetic polymorphisms among different dog breeds. Its isoforms and variations in glycosylation patterns have been explored to understand genetic diversity, metabolic adaptation, and even forensic identification in veterinary science.

Clinically, measuring serum transferrin concentration or transferrin saturation can aid in the diagnosis of iron deficiency anemia, chronic diseases, and liver dysfunction in dogs. It also provides complementary diagnostic information alongside other iron-related markers such as ferritin and total iron-binding capacity (TIBC). Furthermore, transferrin has been investigated as a marker of inflammation and nutritional status, assisting veterinarians in monitoring disease progression and therapeutic response. Thus, canine transferrin serves as both a physiological regulator and a practical diagnostic biomarker in veterinary research and clinical medicine.

This product is manufactured in USA by Eagle Biosciences.