The **Dog sIL-2R ELISA Kit** is designed to measure soluble interleukin-2 receptor (sIL-2R) levels in canine serum, plasma, or other biological samples. sIL-2R is a shed form of the IL-2 receptor α-chain (CD25), released into circulation during T-cell activation. Because it reflects the degree of immune system stimulation, sIL-2R serves as an important biomarker of inflammation, immune dysregulation, and lymphoproliferative activity. Elevated levels are commonly associated with activated T-cell responses, chronic inflammatory conditions, autoimmune disease, and certain cancers such as lymphoma.
In **research settings**, this ELISA kit is used to monitor immune activation in canine models, evaluate immunomodulatory therapies, and study the pathophysiology of inflammatory or neoplastic diseases. It enables investigators to quantify changes in T-cell activation over time and correlate these with disease progression, therapeutic response, or experimental treatment effects. Because sIL-2R is a dynamic marker, it is particularly useful for longitudinal studies examining how interventions modulate cellular immunity.
In **veterinary clinical and preclinical contexts**, measuring sIL-2R can support the assessment of immune-mediated disorders, help differentiate between inflammatory and neoplastic conditions, and provide prognostic insight in diseases such as lymphoma. While not a stand-alone diagnostic tool, sIL-2R levels can complement other clinical findings to guide treatment decisions or monitor disease activity. In translational research, canine sIL-2R data can also inform comparative oncology studies, where dogs serve as valuable models for human immune-related diseases.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.050 ng/ml |
| Dynamic Range | 0.08 – 5 ng/mL |
| Incubation Time | 1 hour 50 minutes |
| Sample Type | Plasma, Serum, Tissue Culture Fluids |
| Storage | 2-8°C |
| Alternative Names | 1. This assay is also known as a **Dog Soluble IL-2 Receptor ELISA Kit**. 2. Many researchers refer to it as a **Canine sIL-2R Detection ELISA Kit**. 3. It may also be called a **Dog Soluble Interleukin-2 Receptor Quantification Kit**. 4. Some protocols describe it as a **Canine sIL2-R Immunoassay Kit**. 5. It is sometimes listed as a **Dog Soluble IL-2R Measurement ELISA Kit**. 6. Another common name is a **Canine Soluble IL-2 Receptor Analysis Kit**. 7. It can also be described as a **Dog sIL-2R Quantitative ELISA Kit**. 8. In some catalogs, it is labeled as a **Canine Soluble IL-2R Detection Assay Kit**. 1. This assay is also known as a **Dog Soluble IL-2 Receptor ELISA Kit**. |