C3 ELISA Kit 2×96 well kit

Complement component 3 (C3) is a central protein in the complement system, a key part of the innate immune response. C3 plays a critical role in pathogen recognition, opsonization, and the activation of downstream complement pathways, ultimately leading to inflammation and clearance of microbes and immune complexes. It is synthesized primarily in the liver and circulates in plasma as an inactive precursor, which can be cleaved into active fragments (C3a and C3b) during complement activation. Abnormal levels of C3 can reflect dysregulation of immune responses, including autoimmune diseases, infections, and inflammatory conditions.

C3 ELISA (enzyme-linked immunosorbent assay) enables quantitative measurement of C3 protein in serum, plasma, or other biological fluids. In research settings, C3 ELISAs are widely used to study complement activation, investigate mechanisms of innate immunity, and explore the role of complement in diseases such as systemic lupus erythematosus, kidney disorders, and infections. Researchers also use C3 measurements to assess immune system responses in experimental therapies, inflammation models, and transplantation studies.

In clinical settings, C3 ELISA is used to evaluate immune function and monitor disease activity in patients with autoimmune disorders, infections, or complement deficiencies. Low C3 levels can indicate complement consumption in diseases like lupus nephritis, while elevated levels may reflect acute-phase responses or inflammation. Monitoring C3 concentrations helps clinicians diagnose complement-related disorders, assess disease severity, and guide treatment strategies, particularly in conditions where complement dysregulation contributes to pathology.

This product is manufactured in USA by Eagle Biosciences.