Bovine Immunoglobulin M (IgM) is a class of antibody found in cattle that plays a crucial role in the early stages of immune response. As a pentameric antibody, IgM is the first immunoglobulin to be produced in response to an antigen, making it a valuable biomarker for detecting recent or acute infections in bovine populations. It is primarily found in serum and colostrum and is involved in agglutination, complement activation, and neutralization of pathogens. Due to its early presence during infection, bovine IgM serves as a key marker for monitoring immune status and exposure to infectious agents such as bovine viral diarrhea virus (BVDV), bovine respiratory syncytial virus (BRSV), and other pathogens.
In research settings, bovine IgM is used to study immune system development, disease pathogenesis, and the efficacy of vaccines in cattle. It is also employed in comparative immunology studies to understand cross-species immune responses and to develop veterinary diagnostics. In clinical and agricultural settings, detection of bovine IgM is commonly used for diagnosing recent infections, ensuring herd health, and improving livestock management practices. Additionally, bovine-derived immunoglobulins, including IgM, are explored for therapeutic uses in humans, such as in passive immunotherapy and gastrointestinal health products, due to their ability to bind and neutralize pathogens without triggering strong immune responses.
This product is manufactured in USA by Eagle Biosciences.
Size | 1 x 96 Well |
Sensitivity | |
Dynamic Range | 12.5 ng/mL – 400 ng/mL |
Incubation Time | 80 minutes |
Sample Type | Serum, plasma |
Immunogen | |
Source Species | |
Specificity | |
Expression System | |
Clone | |
Group | |
Alpha Chain | |
Beta Chain | |
Peptide | |
Peptide Source | |
Format | |
Buffer | |
Concentration | |
Storage | 2-8°C |
Alternative Names | Bovine Immunoglobulin M, Serum IgM (Bovine), Colostral IgM, Natural IgM |
Instructions For Use | https://eaglebio.com/wp-content/uploads/2019/05/RUO_BCM61-K01_Bovine_IgM_ELISA_Assay_Kit_Package_Insert_v4.1.pdf |
MSDS | https://eaglebio.com/wp-content/uploads/2019/05/BCM61-K01-Bovine-IgM-ELISA-Assay-MSDS.pdf |