Bovine Immunoglobulin A (IgA) is a key antibody involved in mucosal immunity in cattle. It is predominantly found in mucosal secretions such as saliva, milk, and the gastrointestinal tract, where it plays a critical role in the first line of defense against pathogens. Secretory IgA helps neutralize viruses and bacteria, prevents microbial adhesion to epithelial surfaces, and modulates the gut microbiota. In neonatal calves, bovine IgA is especially important as part of the passive immunity transferred through colostrum, offering protection until the calf’s own immune system matures.
In research settings, bovine IgA is studied to understand mucosal immune responses, particularly in the context of infectious diseases like bovine respiratory and gastrointestinal infections. It is also used to evaluate the effectiveness of vaccines and feed-based immunostimulants that aim to enhance mucosal immunity. In clinical and veterinary contexts, monitoring IgA levels can help assess immune function in calves, detect mucosal infections, and evaluate colostrum quality for passive transfer. Additionally, bovine IgA is being explored for its potential use in human health, especially in the development of oral immunotherapies and functional foods aimed at supporting gut and immune health.
This product is manufactured in USA by Eagle Biosciences.