Noradrenaline (norepinephrine) and adrenaline (epinephrine) are catecholamine hormones and neurotransmitters that play central roles in the body’s stress response and autonomic regulation. Both are synthesized from the amino acid tyrosine through a shared biosynthetic pathway, with noradrenaline serving as a precursor to adrenaline. Noradrenaline is primarily released from sympathetic nerve endings and the locus coeruleus in the brain, while adrenaline is secreted mainly from the adrenal medulla into the bloodstream. As biomarkers, they reflect sympathetic nervous system activity and adrenal medullary output, providing insight into physiological and psychological stress responses, cardiovascular function, and metabolic regulation.
In research settings, noradrenaline and adrenaline are key biomarkers for studying the neurobiology of stress, emotional regulation, and autonomic dysfunction. Their circulating or urinary levels are frequently measured to assess sympathetic activation in studies of anxiety, depression, cardiovascular disease, and metabolic disorders. Variations in their concentrations or turnover rates can also help elucidate mechanisms underlying stress resilience, fatigue, or neurodegenerative processes. In psychophysiological research, these catecholamines are used to correlate biochemical changes with behavioral and physiological responses such as heart rate, blood pressure, and cognitive performance under stress.
This product is manufactured in Germany by DLD Diagnostika.
| Size | 2 x 96 Well |
| Sensitivity | AdrenaLine (urine): 0.16 ng/mL, (pLasma): 0.85 ng/mL, NoradrenaLine (urine): 8 pg/mL, (pLasma): 43 pg/mL |
| Dynamic Range | AdrenaLine: 0.5 – 250 ng/mL, NoradrenaLine: 1.5 – 500 ng/mL |
| Incubation Time | Overnight |
| Sample Type | Urine, Plasma |
| Storage | 2-8°C |
| Alternative Names | β,3,4-Trihydroxyphenethylamine, Adrenergic neurotransmitter |
