Arginine and ornithine are key amino acids involved in the urea cycle and nitrogen metabolism. Arginine serves as a precursor for nitric oxide, a critical signaling molecule that regulates vascular tone, immune response, and neurotransmission, while ornithine plays a central role in ammonia detoxification and polyamine synthesis. Abnormal levels of these amino acids can indicate metabolic dysfunction, liver disease, or disorders affecting nitric oxide production and cellular growth. Their dynamic interplay makes them important biomarkers for assessing metabolic and physiological status.
The Arginine/Ornithine ELISA allows for sensitive and quantitative measurement of these amino acids in plasma, serum, or other biological samples. In research settings, these assays are widely used to investigate amino acid metabolism, the urea cycle, and nitric oxide-related pathways. Researchers utilize these measurements to study conditions such as cardiovascular disease, liver dysfunction, immune system regulation, and cancer, as well as to evaluate the effects of dietary interventions or pharmacological treatments on amino acid homeostasis.
Clinically, monitoring arginine and ornithine levels can aid in diagnosing metabolic disorders, such as urea cycle deficiencies, and in assessing the nutritional and metabolic status of patients. ELISA-based measurements provide a convenient and reliable tool for evaluating therapy efficacy, detecting early metabolic imbalances, and guiding treatment decisions in conditions where amino acid metabolism plays a pivotal role.
This product is manufactured in by ImmuSmol.
| Size | 2 x 96 Well |
| Sensitivity | Arg: 2.1µM Orn: 8.5µM |
| Dynamic Range | Arg: 5.12 – 200µM Orn: 20 – 781.25µM |
| Incubation Time | Overnight |
| Sample Type | Plasma, serum |
| Alternative Names | L-arginine and 2-amino-5-guanidinopentanoic acid, L-ornithine and 2,5-diaminovaleric acid. |
