Anti-FGFR-3 Autoantibodies ELISA Kit
The Anti-FGFR-3 Autoantibodies ELISA Kit is designed to detect autoantibodies directed against fibroblast growth factor receptor 3 (FGFR-3), a transmembrane tyrosine-kinase receptor involved in cell growth, differentiation, and tissue maintenance. FGFR-3 plays an important role in skeletal development and is expressed in various tissues, including cartilage, skin, and the nervous system. Autoantibodies targeting FGFR-3 have been associated with certain neuropathies and autoimmune conditions, making their detection useful for both clinical research and mechanistic studies.
In a typical ELISA format, recombinant FGFR-3 or its relevant antigenic domain is coated onto a microplate to capture FGFR-3–specific autoantibodies from serum or plasma samples. Bound autoantibodies are then detected with enzyme-linked secondary antibodies that produce a colorimetric signal proportional to their concentration. This standardized setup allows researchers to quantify autoantibody levels with high sensitivity and reproducibility.
Applications of the Anti-FGFR-3 Autoantibodies ELISA Kit include investigating autoimmune mechanisms in sensory or motor neuropathies, evaluating biomarkers for disease diagnosis or progression, and exploring the role of FGFR-3–directed immune responses in broader inflammatory or degenerative conditions. Because FGFR-3 signaling influences neural and musculoskeletal physiology, the presence of these autoantibodies can provide valuable insights into disease pathways and potential therapeutic targets.
This Anti-FGFR-3 Autoantibodies ELISA Kit is manufactured in Germany by CellTrend GmbH.
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