Rat L-FABP ELISA Kit
The **Rat L-FABP (Liver Fatty Acid–Binding Protein) ELISA Kit** measures levels of L-FABP, a small cytoplasmic protein highly expressed in hepatocytes and proximal renal tubular cells. L-FABP binds long-chain fatty acids and helps regulate lipid metabolism and oxidative stress responses. Because it is rapidly released into circulation or urine following hepatocellular injury or renal tubular damage, L-FABP has emerged as a sensitive biomarker for early organ injury—often rising before traditional markers such as ALT, AST, or creatinine.
In **research settings**, the Rat L-FABP ELISA Kit is widely used in studies of liver toxicity, nonalcoholic fatty liver disease (NAFLD), ischemia–reperfusion injury, drug-induced hepatotoxicity, and metabolic disorders. Its sensitivity makes it valuable for detecting subtle or early-stage hepatic stress in toxicology studies. Additionally, because L-FABP is also a marker of proximal tubular injury, it is employed in nephrology research to evaluate kidney damage in models of acute kidney injury, chronic kidney disease, and exposure to nephrotoxic compounds.
In **preclinical and translational applications**, measuring L-FABP helps assess the safety profiles of pharmaceuticals, chemicals, and biologics by providing early indication of liver or renal toxicity. Although L-FABP testing in rats is not used directly for clinical diagnoses in humans, its behavior parallels L-FABP biology across species, making it a valuable surrogate for predicting potential organ injury risks and informing dose selection, therapeutic monitoring strategies, and clinical trial design.
This Rat L-FABP ELISA Kit is manufactured in USA by Eagle Biosciences.
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