Mouse C1q ELISA Kit
C1q is a key recognition molecule of the classical complement pathway, playing a central role in innate immunity by binding to the Fc region of antibodies in immune complexes and initiating complement activation. Beyond its immune functions, C1q is involved in the clearance of apoptotic cells, modulation of inflammation, and tissue homeostasis. Dysregulation of C1q has been associated with autoimmune disorders, such as systemic lupus erythematosus (SLE), and neurodegenerative diseases, where it may contribute to abnormal synaptic pruning. Its presence and activity in serum or tissue make it an important biomarker for studying complement-mediated processes in both health and disease.
Mouse C1q ELISA is an enzyme-linked immunosorbent assay designed to quantitatively measure C1q levels in mouse serum, plasma, or cell culture supernatants. In research settings, this assay is widely used to study the role of the classical complement pathway in immune responses, autoimmune disease models, infection, and tissue injury. It allows researchers to monitor changes in C1q expression during experimental interventions, evaluate complement activity, and investigate mechanisms of immune complex clearance and inflammation in preclinical models.
Although primarily used in research, mouse C1q ELISA also has translational relevance for clinical studies that rely on mouse models. By accurately quantifying C1q levels, researchers can better understand disease mechanisms, evaluate potential therapeutics targeting complement activation, and validate biomarkers before moving into human studies. This makes it an essential tool for bridging preclinical findings to potential clinical applications in immunology, autoimmune disease, and inflammatory research.
This Mouse C1q ELISA Kit is manufactured in USA by Eagle Biosciences.
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