M1 AChR ELISA Kit

The M1 Acetylcholine Receptor (M1 AChR) ELISA Kit is designed to detect and quantify antibodies against the M1 muscarinic acetylcholine receptor (M1 AChR), a G-protein–coupled receptor widely expressed in the central nervous system and peripheral tissues. M1 AChR plays a critical role in cognitive function, memory, and neuronal signaling. Autoantibodies targeting M1 AChR have been implicated in autoimmune neurological disorders, neurodegenerative diseases, and certain forms of dysautonomia, making their detection valuable for both research and clinical studies.

In this ELISA assay, microplate wells are coated with recombinant or synthetic M1 AChR antigens to capture specific antibodies from serum, plasma, or other biological samples. After binding, an enzyme-linked secondary antibody produces a colorimetric signal proportional to the concentration of M1 AChR–specific antibodies. This method provides a sensitive, specific, and reproducible approach for quantifying receptor-targeting antibodies in preclinical or clinical research.

Applications of the M1 AChR ELISA Kit include investigating autoimmune-mediated neurological dysfunction, monitoring antibody responses in neurodegenerative or cognitive disorders, and studying receptor-targeting antibodies in experimental models. Measuring these antibodies provides insights into disease mechanisms, immune-mediated receptor modulation, and potential therapeutic interventions targeting cholinergic signaling pathways.

This product is manufactured in Germany by CellTrend GmbH.