The Anti–Beta-2 Adrenergic Receptor Antibodies (IgG) ELISA Kit is designed to detect and quantify IgG-class autoantibodies directed against the Beta-2 adrenergic receptor (Beta-2 AR), a key G-protein–coupled receptor involved in smooth-muscle relaxation, cardiovascular modulation, and pulmonary function. Because the Beta-2 AR plays a central role in bronchodilation and vascular tone regulation, autoantibodies targeting this receptor have become increasingly important in research on dysautonomia, autoimmune diseases, and chronic inflammatory conditions.
In this ELISA system, synthetic peptides or recombinant extracellular domains of the Beta-2 AR are immobilized on a microplate to capture Beta-2 AR–specific IgG from serum samples. After binding occurs, an enzyme-linked secondary antibody generates a colorimetric signal proportional to the concentration of the target autoantibodies. This setup offers a sensitive, specific, and reproducible platform suitable for both focused mechanistic studies and broader research applications.
The Anti–Beta-2 Adrenergic Receptor Antibodies (IgG) ELISA Kit is commonly used to investigate immune involvement in autonomic dysfunction, characterize biomarker profiles in disorders such as chronic fatigue syndrome or fibromyalgia, and evaluate Beta-2 AR–related autoimmunity in cardiovascular or pulmonary research. Because the Beta-2 AR influences multiple physiological systems, measuring these autoantibodies can yield valuable insights into disease mechanisms, immune dysregulation, and potential therapeutic targets.
This product is manufactured in Germany by CellTrend GmbH.
| Size | 1 x 96 Well |
| Sensitivity | 2.5 U/mL |
| Dynamic Range | 2.5 – 40 U/mL |
| Incubation Time | 3 hours 30 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | beta2 adrenergic receptor autoantibodies, beta2 AR–reactive IgG, anti–beta2 AR IgG, beta2 receptor–targeting autoantibodies, or beta2 adrenergic receptor–specific IgG antibodies |
