The Hamster (CHO) Nidogen-1 ELISA Kit is designed to quantitatively measure nidogen-1, a key extracellular matrix (ECM) glycoprotein involved in basement membrane structure and stability. Nidogen-1 (also known as entactin) serves as a bridging molecule that links laminin, collagen IV, and other ECM components, making it essential for maintaining tissue architecture and cell–matrix interactions. Changes in nidogen-1 expression or secretion can reflect alterations in ECM integrity, cellular stress, or remodeling processes. Using ELISA technology, researchers can sensitively detect nidogen-1 levels in CHO (Chinese Hamster Ovary) cell culture supernatants or hamster-derived biological samples.
In research settings, the Hamster/CHO Nidogen-1 ELISA Kit is especially valuable for studies utilizing CHO cells, a widely used platform for biopharmaceutical production. Monitoring nidogen-1 levels can serve as an indicator of cell line health, stability, and extracellular matrix organization during bioprocess development. It is also useful in investigations of basement membrane biology, cell adhesion, tissue engineering, and models of fibrosis or tumor progression where ECM proteins play a central role. Because CHO cells are central to recombinant protein and monoclonal antibody production, quantifying nidogen-1 can help optimize culture conditions and understand ECM-related changes that influence productivity and cell viability.
Although the kit is not intended for direct clinical diagnostic use, data generated from CHO or hamster studies contribute to translational research on ECM remodeling in diseases such as cancer, fibrosis, and tissue degeneration. Understanding nidogen-1 behavior in controlled experimental systems helps guide biomarker discovery and therapeutic development targeting the basement membrane and ECM pathways. Consequently, the Hamster (CHO) Nidogen-1 ELISA Kit provides a powerful tool for bridging fundamental ECM research with applications relevant to biomedical and biomanufacturing settings.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.101 ng/ml |
| Dynamic Range | 0.3125 ng/mL – 20 ng/mL |
| Incubation Time | 2 hours 50 minutes |
| Sample Type | Tissue Culture Fluids |
| Storage | 2-8°C |
| Alternative Names | * This assay is also known as the **Hamster (CHO) Nidogen-1 Quantification ELISA Kit**. * Researchers may refer to it as the **Hamster (CHO) Nidogen-1 Immunoassay Kit**. * It is sometimes called the **Hamster (CHO) Nidogen-1 ELISA Detection Kit**. * Some suppliers label it as the **Hamster (CHO) Nidogen-1 Sandwich ELISA Kit**. * Another common name for it is the **Hamster (CHO) Nidogen-1 Measurement Kit**. |