The Mouse IgG2c ELISA Kit is designed to quantitatively measure immunoglobulin G2c (IgG2c) in mouse serum, plasma, or other biological samples. IgG2c is an IgG subclass found in certain mouse strains—most notably C57BL/6 and related strains—where it functionally replaces IgG2a. This subclass is associated with Th1-type immune responses and is often used as an indicator of cellular immunity, antiviral activity, and responses to intracellular pathogens. Because IgG2c levels can reflect the balance between Th1 and Th2 immune pathways, measuring this antibody subclass provides valuable insight into immune polarization and vaccine-induced immunity.
In research settings, the Mouse IgG2c ELISA Kit is commonly used in studies focused on infectious diseases, vaccine development, autoimmune disorders, and immunomodulation. Quantifying IgG2c helps researchers evaluate humoral immune responses following vaccination, antigen exposure, or therapeutic interventions. It is particularly useful when comparing Th1-driven IgG2c responses with Th2-associated IgG1 levels to assess immune skewing. The assay’s sensitivity and specificity make it ideal for longitudinal studies tracking antibody production over time or comparing immune profiles across experimental groups.
Although the kit itself is not used in clinical diagnostics, IgG subclass analysis in mouse models is highly relevant for translational immunology. Mouse IgG2c responses help predict the type and strength of immune responses expected from novel vaccines, adjuvants, and immunotherapies in humans. These studies support preclinical decision-making by identifying promising immune signatures, optimizing dosing, and assessing potential adverse immune reactions. Overall, the Mouse IgG2c ELISA Kit is an essential tool for exploring adaptive immunity and guiding the development of next-generation vaccines and immunomodulatory treatments.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.397 ng/mL |
| Dynamic Range | 3.125 ng/mL – 200 ng/mL |
| Incubation Time | 1 hour 10 minutes |
| Sample Type | Plasma, Serum |
| Storage | 2-8°C |
| Alternative Names | * This assay is also known as the **Mouse IgG2c Quantification ELISA Kit**. * Researchers may refer to it as the **Mouse IgG2c Immunoassay Kit**. * It is sometimes called the **Mouse IgG2c ELISA Detection Kit**. * Some suppliers label it as the **Mouse IgG2c Sandwich ELISA Kit**. * Another common name for it is the **Mouse IgG2c Measurement Kit**. |