The Mouse IgG2b ELISA Kit is designed to quantitatively measure immunoglobulin G2b (IgG2b) in mouse serum, plasma, or other biological samples. IgG2b is one of the key subclasses of IgG in mice and plays an important role in humoral immunity, particularly in responses involving complement activation, antibody-dependent cellular cytotoxicity (ADCC), and protection against intracellular pathogens. Levels of IgG2b often reflect the balance between Th1- and Th2-mediated immune responses, making it a useful biomarker for understanding immune polarization. ELISA-based detection provides a sensitive and specific method for profiling IgG2b dynamics during immune challenges or experimental manipulation.
In research settings, the Mouse IgG2b ELISA Kit is frequently used to assess antigen-specific antibody responses in vaccine development, infectious disease models, and immunotherapy studies. By quantifying IgG2b, researchers can evaluate class-switch recombination, characterize the quality of humoral responses, and compare immune signatures across different treatment groups or experimental conditions. It is also useful in autoimmune and inflammatory disease models, where shifts in IgG subclasses—including IgG2b—may indicate changes in disease progression or immune modulation.
Although the kit is not used directly in clinical diagnostics, data obtained from mouse IgG2b measurements contribute to translational research by illustrating how specific antibody subclasses correlate with protective immunity or pathological immune activation. Insights from mouse studies help guide vaccine formulation, therapeutic antibody development, and strategies for modulating immune responses in human diseases. Thus, the Mouse IgG2b ELISA Kit serves as a valuable tool for characterizing adaptive immunity and advancing preclinical research with clinical relevance.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.878 ng/mL |
| Dynamic Range | 6.25 ng/mL – 200 ng/mL |
| Incubation Time | 1 hour 10 minutes |
| Sample Type | Plasma, Serum |
| Storage | 2-8°C |
| Alternative Names | * This assay is also known as the **Mouse IgG2b Quantification ELISA Kit**. * Researchers may refer to it as the **Mouse IgG2b Immunoassay Kit**. * It is sometimes called the **Mouse IgG2b ELISA Detection Kit**. * Some suppliers label it as the **Mouse IgG2b Sandwich ELISA Kit**. * Another common name for it is the **Mouse IgG2b Measurement Kit**. |