B2M ELISA Kit

Beta-2 Microglobulin (B2M) is a low-molecular-weight protein that forms the light chain component of major histocompatibility complex (MHC) class I molecules, present on the surface of nearly all nucleated cells. It is released into the bloodstream during normal cell turnover and at higher levels during increased cellular activation or turnover, such as inflammation, malignancy, or infection. Because B2M is filtered by the kidneys, its serum and urine concentrations are also closely associated with renal function. The B2M ELISA Kit enables precise quantification of B2M levels in serum, plasma, urine, or other biological fluids, offering a sensitive method for assessing immune activation, renal integrity, and disease progression.

In research settings, B2M is widely used as a biomarker to study immune system activation, tumor burden, and renal physiology. Elevated B2M levels are observed in various conditions, including autoimmune diseases, viral infections (e.g., HIV, hepatitis), hematologic malignancies (such as multiple myeloma and lymphoma), and chronic kidney disease. Clinically, B2M measurement aids in evaluating renal tubular function, monitoring certain cancers, and serving as a prognostic marker for disease severity or treatment response. Overall, the B2M ELISA Kit is a valuable tool for both research and clinical applications, providing insights into immune activity, renal health, and systemic disease processes.

This product is manufactured in USA by Eagle Biosciences.