The Apolipoprotein A1 (ApoA1) ELISA Kit is designed to quantitatively measure ApoA1, the major protein component of high-density lipoprotein (HDL) particles. ApoA1 plays a central role in cholesterol transport by activating lecithin–cholesterol acyltransferase (LCAT), an enzyme crucial for HDL maturation and reverse cholesterol transport. Because ApoA1 reflects HDL function rather than just HDL quantity, it serves as an important biomarker for cardiovascular health, lipid metabolism, and inflammatory processes. ELISA-based detection allows sensitive and reproducible measurement of ApoA1 across various biological samples, including serum, plasma, and cell culture media.
In research settings, ApoA1 ELISA Kits are used to study lipid metabolism, atherosclerosis, metabolic syndrome, and cardiovascular disease models. Investigators use them to monitor how dietary interventions, genetic modifications, therapeutics, or metabolic stressors affect HDL function and ApoA1 levels. ApoA1 is also evaluated in studies involving liver function, as it is synthesized primarily in the liver and intestines. Beyond cardiovascular research, ApoA1 is examined as a potential biomarker in inflammation, infection, and certain cancers, where changes in lipid metabolism are linked to disease progression.
In clinical and translational research, ApoA1 measurements contribute to evaluating cardiovascular risk, particularly when used alongside ApoB or HDL-cholesterol. Although ELISA kits are typically intended for research use only, data from such studies help improve biomarker panels for predicting coronary artery disease and guiding lipid-lowering therapies. ApoA1 is also being explored as a biomarker for early detection or monitoring of conditions such as Alzheimer’s disease, because altered lipid transport can influence neurodegeneration. Overall, the ApoA1 ELISA Kit provides a versatile tool for advancing understanding of lipid biology and supporting development of clinically relevant diagnostics and therapeutics.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 4.022 ng/ml |
| Dynamic Range | 15.6 ng/ml – 500 ng/ml |
| Incubation Time | 1 hour 40 minutes |
| Sample Type | Plasma, Serum |
| Storage | 2-8°C |
| Alternative Names | * This assay is also known as the **Apolipoprotein A1 Quantification ELISA Kit**. * Researchers may refer to it as the **Apolipoprotein A1 Immunoassay Kit**. * It is sometimes called the **Apolipoprotein A1 ELISA Detection Kit**. * Some suppliers label it as the **Apolipoprotein A1 Sandwich ELISA Kit**. * Another common name for it is the **Apolipoprotein A1 Measurement Kit**. |