N8-Acetyl-Spermidine ELISA Kit

N8-Acetyl Spermidine is a naturally occurring acetylated derivative of spermidine, a polyamine involved in cellular growth, differentiation, and apoptosis. Polyamines like spermidine play essential roles in stabilizing DNA, modulating gene expression, and regulating cellular proliferation. The acetylated form, N8-Acetyl Spermidine, reflects polyamine metabolism and turnover, making it a useful biomarker for altered cellular activity, particularly in rapidly dividing or stressed cells. Changes in N8-Acetyl Spermidine levels have been associated with cancer, neurodegenerative disorders, and other pathological conditions involving dysregulated cell growth or apoptosis.

The N8-Acetyl Spermidine ELISA (enzyme-linked immunosorbent assay) allows for the sensitive and specific quantification of this biomarker in biological samples such as serum, plasma, or tissue extracts. In research settings, it is used to study polyamine metabolism, cell proliferation, and apoptosis pathways, as well as to explore the role of polyamines in cancer progression, neurodegeneration, and metabolic disorders. By measuring N8-Acetyl Spermidine, researchers can gain insights into cellular stress responses and evaluate the impact of experimental drugs or interventions on polyamine dynamics.

In clinical applications, N8-Acetyl Spermidine ELISAs have potential utility as a diagnostic or prognostic biomarker, particularly in oncology and metabolic disease monitoring. Elevated or altered levels may indicate abnormal cell proliferation or tumor activity, helping to guide therapeutic decisions or monitor treatment efficacy. Additionally, the assay can support studies on disease progression and patient response in conditions where polyamine metabolism is disrupted, providing a non-invasive tool for clinical assessment and longitudinal monitoring.

This product is manufactured in by ImmuSmol.