Ferritin is an iron-storage protein that plays a central role in regulating iron homeostasis by storing excess iron and releasing it in a controlled manner. In rats, as in other mammals, ferritin is found in most tissues and circulates at low levels in the blood, reflecting the body’s iron stores. Because iron is essential for numerous physiological processes, including oxygen transport, DNA synthesis, and cellular metabolism, ferritin serves as a sensitive biomarker for iron availability and metabolic status. Its levels can be influenced by iron deficiency, inflammation, infection, and liver function, making it a valuable indicator of both nutritional and pathological states.
The rat ferritin ELISA is a sensitive immunoassay designed to quantitatively measure ferritin concentrations in serum, plasma, or tissue samples. In research settings, it is commonly used to study iron metabolism, anemia, inflammation, and the effects of experimental interventions on iron homeostasis. Researchers also use ferritin measurements to investigate the relationship between iron regulation and chronic diseases, including cardiovascular disorders, neurodegeneration, and cancer models in rats.
In clinical and preclinical contexts, measuring ferritin levels can help detect iron deficiency or overload, assess systemic inflammation, and monitor the efficacy of treatments affecting iron metabolism. While primarily a research tool in rat models, ferritin ELISA data can provide insights relevant to human health, including understanding disease mechanisms, testing therapeutic strategies, and evaluating nutritional interventions in translational studies.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 3.014 ng/mL |
| Dynamic Range | 12.5 ng/mL – 400 ng/mL |
| Incubation Time | 1 hour 20 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Ferritin heavy chain, ferritin light chain, L-ferritin, H-ferritin, and iron storage protein. |