Canine complement component 3 (C3) is a central protein in the complement system, a key part of the innate immune response that helps the body recognize and eliminate pathogens. C3 plays a pivotal role in all three complement activation pathways—classical, lectin, and alternative—by mediating opsonization, promoting phagocytosis, and triggering the formation of the membrane attack complex. In dogs, as in other species, C3 levels reflect the activity and integrity of the complement system, and abnormal levels can indicate immune dysregulation, infection, or inflammatory disease.
The canine C3 ELISA allows for the quantitative measurement of C3 in serum, plasma, or other biological samples. In research, this assay is used to study immune function, investigate the pathophysiology of inflammatory and autoimmune diseases, and evaluate the impact of experimental therapies on the complement system. It also helps researchers understand breed-specific differences in immune response and susceptibility to infections or immune-mediated disorders.
Clinically, canine C3 measurement can aid in diagnosing and monitoring diseases involving complement activation, such as autoimmune hemolytic anemia, glomerulonephritis, and systemic inflammatory conditions. The ELISA provides veterinarians with a sensitive tool to assess immune status, track disease progression, and evaluate responses to treatment. By quantifying C3, clinicians can gain insights into both acute inflammatory responses and chronic immune-mediated processes in canine patients.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.947 ng/mL |
| Dynamic Range | 6.25 – 200 ng/mL |
| Incubation Time | 50 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Complement component 3, C3 complement, complement C3, C3 protein, and complement factor 3. |