Beta-2 Microglobulin (B2M) is a small, non-glycosylated protein that forms the light chain of major histocompatibility complex (MHC) class I molecules, which are expressed on the surface of almost all nucleated cells. In hamster CHO (Chinese Hamster Ovary) cells, B2M plays a similar role in immune recognition and cellular signaling. It is released into the culture medium during normal cell turnover or under stress conditions, making it a useful biomarker for monitoring cell health, immune activity, and protein expression in CHO-based experimental systems. The Hamster CHO B2M ELISA Kit is designed to quantitatively measure B2M levels in cell culture supernatants, lysates, or other biological samples, providing a sensitive and reliable method for assessing cellular processes in preclinical research.
In research applications, this ELISA kit is widely used in studies involving CHO cells, which are a common model for protein production, gene expression, and biopharmaceutical development. Measuring B2M levels allows researchers to monitor cell viability, immune-related responses, and stress-induced protein release, which can be critical when optimizing cell culture conditions or evaluating the effects of treatments. While primarily a research tool, data from B2M measurement in CHO cells can inform translational studies, particularly those related to protein therapeutics, immunogenicity, and cell-based disease modeling.
Although the Hamster CHO B2M ELISA Kit is not directly used in clinical diagnostics, it provides essential preclinical insights relevant to human health. B2M is a clinically important biomarker in humans for renal function, immune activation, and certain malignancies. By studying B2M dynamics in CHO cells, researchers can better understand protein expression, secretion pathways, and cellular responses, which ultimately supports drug development, biomarker discovery, and translational research bridging preclinical and clinical applications.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.822 ng/ml |
| Dynamic Range | 0.3125 – 20 ng/mL |
| Incubation Time | 2 hours 50 minutes |
| Sample Type | Tissue Culture Fluids |
| Storage | 2-8°C |
| Alternative Names | Hamster B2M ELISA kit, CHO Beta-2-microglobulin ELISA kit, Chinese hamster B2M ELISA kit, hamster Beta-2-microglobulin immunoassay kit, CHO B2-microglobulin quantitative ELISA kit, hamster B2M detection kit, Chinese hamster Beta-2M assay kit, hamster B2M sandwich ELISA kit, CHO Beta-2M ELISA kit, hamster Beta-2-microglobulin quantification kit. |