Feline (Cat) IgA ELISA Kit

Immunoglobulin A (IgA) in cats is a key antibody involved in mucosal immunity, primarily found in mucous secretions such as saliva, tears, intestinal fluid, and respiratory tract secretions. Like in other species, feline IgA exists in both serum (monomeric form) and secretory (dimeric) forms, with the secretory form playing a vital role in the first line of defense against pathogens entering through mucosal surfaces. It is produced mainly by plasma cells in mucosal-associated lymphoid tissues (MALT) and transported across epithelial cells via the polymeric immunoglobulin receptor (pIgR). Structurally and functionally, feline IgA shares similarities with other mammalian IgAs, although species-specific differences exist in its molecular composition and immune activity.

In research, feline IgA serves as an important biomarker for studying mucosal immune responses, vaccine efficacy, and host–pathogen interactions in the respiratory and gastrointestinal tracts. Quantifying IgA levels can help evaluate the effectiveness of mucosal vaccines or investigate immune dysregulation in conditions such as feline inflammatory bowel disease (IBD), chronic gingivostomatitis, and upper respiratory infections.

Clinically, measurement of feline IgA can provide insights into the integrity and function of the mucosal immune system. Decreased serum or mucosal IgA concentrations may indicate immunodeficiency syndromes, while elevated levels can be associated with chronic inflammatory or infectious diseases. Therefore, feline IgA is a valuable biomarker for both diagnostic and research applications, contributing to a better understanding of feline immune health and guiding therapeutic or preventive strategies in veterinary medicine.

This product is manufactured in USA by Eagle Biosciences.