Canine (Dog) IgG ELISA Kit

Canine Immunoglobulin G (IgG) is the most abundant antibody isotype in the serum of dogs and plays a central role in the adaptive immune response. It is produced by plasma cells in response to antigen exposure and provides long-term immunity by neutralizing pathogens, facilitating opsonization, and activating the complement system. Structurally and functionally, canine IgG shares many similarities with IgG in other mammals, though it exhibits subclass variations (e.g., IgG-A, IgG-B, etc.) that differ in their effector functions and affinities for immune receptors. These differences can influence how dogs respond to infections, vaccinations, or autoimmune conditions.

In research settings, canine IgG serves as a valuable biomarker for monitoring immune responses in studies involving infectious diseases, vaccine development, and immunotherapy. Quantifying IgG levels using assays such as ELISA helps assess exposure to specific pathogens, evaluate vaccine efficacy, and investigate immunopathological mechanisms. In translational research, canine models are also used to study immune-mediated diseases that parallel human conditions, making canine IgG an important tool for comparative immunology.

Clinically, measurement of canine IgG is used to diagnose and monitor various conditions, including immune deficiencies, chronic infections, and autoimmune diseases. Detection of pathogen-specific IgG antibodies can confirm prior exposure or vaccination status, while abnormal total IgG levels may indicate immune dysregulation. Additionally, purified canine IgG and anti-canine IgG reagents are used in diagnostic test development, therapeutic monitoring, and veterinary immunodiagnostics—supporting both clinical decision-making and the advancement of veterinary biomedical research.

This product is manufactured in USA by Eagle Biosciences.