Mouse Monoclonal Antibody to S-Adenosylhomocysteine Clone 301-3
The Mouse Monoclonal Antibody to S-Adenosylhomocysteine Clone 301-3 is For Research Use Only
Size: 50 uL
Form: Liquid
Storage Instructions: Store at 4°C, -20°C for long term storage
Storage Buffer: PBS 10mM pH 7.4 (NaCl 150mM), Sodium azide 0.02%, BSA 10mg/ml or PBS 10mM pH 7.4 (NaCl 150mM), Sodium azide 0.02%, Glycerol 50%, BSA 10mg/ml
Purity: >95% Purified from mouse ascites fluid by affinity chromatography
Clonality: Monoclonal
Clone Number: 301-3
Immunoglobin Isotype: IgG3
Affinity: Ka = 8.32 x 108L/mol (1.20 x 10-9M)
Specificity: Shows the following reactivities with related compounds: S-Adenosylhomocysteine: 100%, S-Adenosylmethionine: 1.5%, Adenosine: <1%, Homocysteine:<1%,L-Cysteine:<1%,Glutathione:<1%,L-Cystathionine: <1%.
Immunogen: S-Adenosylhomocysteine conjugated to BSA
Applications: The application notes include recommended starting dilutions. Optimal dilutions/concentrations should be determined by the end user. Higher dilution than suggested maybe used in IHC and IF. The product may be used in other not-yet-tested applications.
cELISA 1:4000/8000
FCM 1:200
IHC 1:200
Target
S-adenosylhomocysteine is a competitive inhibitor of S-adenosylmethionine-dependant methyl transferase reactions. Therefore, it plays a key role in the control of methylation via regulation of the intracellular concentration of S-adenosylhomocysteine.
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