Mouse Monoclonal Antibody to S-Adenosylhomocysteine Clone 301-1
The Mouse Monoclonal Antibody to S-Adenosylhomocysteine Clone 301-1 is For Research Use Only
Storage Instructions: Store at 4°C, -20°C for long term storage
Storage Buffer: PBS 10mM pH 7.4 (NaCl 150mM), Sodium azide 0.02%, BSA 10mg/ml or PBS 10mM pH 7.4 (NaCl 150mM), Sodium azide 0.02%, Glycerol 50%, BSA 10mg/ml
Purity: >95% Purified from mouse ascites fluid by affinity chromatography
Clone Number: 301-1
Immunoglobin Isotype: IgG3
Affinity: Ka = 2.778 x 108L/mol (3.60 x 10-9M)
Specificity: Shows the following reactivities with related compounds: S-Adenosylhomocysteine: 100%, S-Adenosylmethionine: 1.5%, Adenosine: <1%, Homocysteine: <1%,L-Cysteine: <1%, Glutathione: <1%, L-Cystathionine: <1%.
Immunogen: S-Adenosylhomocysteine conjugated to BSA
Applications: The application notes include recommended starting dilutions. Optimal dilutions/concentrations should be determined by the end user. Higher dilution than suggested maybe used in IHC and IF. The product may be used in other not-yet-tested applications.
cELISA: 1:4000 / 8000
S-adenosylhomocysteine is a competitive inhibitor of S-adenosylmethionine-dependant methyl transferase reactions. Therefore, it plays a key role in the control of methylation via regulation of the intracellular concentration of S-adenosylhomocysteine.