Adrenaline (Epinephrine) ELISA Assay Kit

$520.00

The Eagle Biosciences Adrenaline (Epinephrine) ELISA Kit is intended for the quantitative determination of Adrenaline in urine or plasma. The Adrenaline (Epinephrine) ELISA Kit is for research use only and not to be used in clinical, therapeutic or diagnostic procedures.

SKU: ADR31-K01 Categories: , , Tag:

Adrenaline (Epinephrine) ELISA Assay Kit

For Research Use Only

Size: 1×96 wells
Sensitivity: Urine: 0.08 ng/ml, Plasma: 5 pg/ml
Dynamic Range: 0.5 – 250 ng/ml (2.7 – 1365 nmol/L)
Incubation Time: Overnight
Sample Type: Urine, Plasma
Sample Size: 15 µL (Urine), 300 µl (Plasma)

Controls Included

Product Developed and Manufactured in Germany by DLD Diagnostika EA604/96


Additional Information

Assay Background


Catecholamine is the name of a group of aromatic amines (noradrenaline, adrenaline, dopamine, and their derivatives) which act as hormones and neurotransmitters, respectively. Adrenaline and noradrenaline are formed from dopamine. They act on the cardiac musculature and the metabolism (adrenaline) as well as on the peripheral circulation (noradrenaline) and help the body to cope with acute and chronic stress.

An increased production of catecholamines can be found with tumors of the chromaffine system (pheochromocytoma, neuroblastoma, ganglio­neuroma). Studies show that an increased or decreased concentration of the catechol­amines can also be found with hypertension, degenerative cardiac diseases, schizophrenia and manic-depressive psychosis.

The Adrenaline (Epinephrine) ELISA Kit provides materials for the quantitative measurement of adrenaline in plasma and urine. Adrenaline is extracted using a cis-diol-specific affinity gel and acylated to N-acyladrenaline and then converted enzymatically into N-acylmetanephrine.

Typical Standard Curve


Manual

Product Manual


Publications

Publications


Armstead, W.M. & Vavilala, M.S. Neurocrit Care (2019). https://doi.org/10.1007/s12028-019-00735-2

Citations


Vali, P;Chandrasekharan, P;Rawat, M;Gugino, S;Koenigsknecht, C;Helman, J;Jusko, WJ;Mathew, B;Berkelhamer, S;Nair, J;Wyckoff, MH;Lakshminrusimha, S;, (2017). Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest. J Am Heart Assoc, 6(2). PubMed: 28214793