Rat Clusterin ELISA Kit

Clusterin, also known as apolipoprotein J, is a multifunctional glycoprotein expressed in many tissues and secreted into bodily fluids. It plays diverse roles in processes such as apoptosis, lipid transport, complement inhibition, and tissue remodeling. In the central nervous system, clusterin is involved in neuroprotection and clearance of cellular debris, while in peripheral tissues it contributes to immune regulation and responses to stress or injury. Its expression is often upregulated under conditions of inflammation, oxidative stress, or tissue damage, making it a valuable biomarker for physiological and pathological changes in the body.

The Rat Clusterin ELISA is a sensitive immunoassay designed to quantify clusterin levels in rat serum, plasma, or tissue samples. In research settings, this assay is commonly used to study the role of clusterin in neurodegenerative diseases, cardiovascular conditions, cancer, and kidney injury, as well as to investigate mechanisms of apoptosis and tissue remodeling. Researchers can monitor changes in clusterin expression in response to experimental treatments, genetic modifications, or disease models, providing insight into underlying molecular pathways.

In a clinical or preclinical context, measuring clusterin levels in rats can help model human disease processes, evaluate potential therapeutic interventions, and assess biomarkers of tissue injury or stress. Elevated or altered clusterin concentrations may indicate ongoing inflammation, cellular stress, or early pathological changes, making it a useful tool for preclinical drug development and translational studies aimed at understanding disease progression or evaluating treatment efficacy.

This product is manufactured in USA by Eagle Biosciences.