Retinol Binding Protein (RBP) is a small plasma protein primarily responsible for the transport of vitamin A (retinol) from the liver to peripheral tissues. As a carrier of retinol, RBP plays a critical role in vision, immune function, and cellular growth and differentiation. Its levels in blood are influenced by nutritional status, kidney function, and liver health, making it a sensitive biomarker for vitamin A deficiency and other metabolic conditions. Beyond its role in retinol transport, RBP has also been implicated in metabolic regulation and insulin resistance, highlighting its broader significance in systemic physiology.
RBP ELISA is a sensitive and specific method for quantifying RBP concentrations in serum, plasma, or urine. In research settings, RBP ELISA is commonly used to study vitamin A metabolism, nutritional status, and metabolic disorders, as well as to investigate its role in conditions like obesity, diabetes, and cardiovascular disease. In clinical settings, measuring RBP levels can assist in assessing vitamin A deficiency, monitoring nutritional interventions, and evaluating kidney function, as RBP is freely filtered by the glomerulus and reabsorbed by the proximal tubules. Its application in both research and clinical diagnostics makes it a versatile biomarker for understanding nutritional and metabolic health.
Because RBP reflects both vitamin A status and renal handling of proteins, it provides valuable insights in studies of malnutrition, chronic kidney disease, and metabolic syndrome. ELISA-based quantification allows for high-throughput and reproducible measurements, facilitating both population-level nutritional assessments and individual patient monitoring. Its dual role as a nutritional and metabolic biomarker makes RBP a critical tool in bridging basic research with clinical applications.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 1.163 ng/mL |
| Dynamic Range | 3.125 ng/mL – 100 ng/mL |
| Incubation Time | 1 hour 20 minutes |
| Sample Type | Serum, plasma, urine |
| Storage | 2-8°C |
| Alternative Names | RBP4, plasma retinol-binding protein, or vitamin A–binding protein. |

