Rat Plasminogen ELISA Kit

Plasminogen is a critical zymogen in the fibrinolytic system, acting as the inactive precursor of plasmin, the enzyme responsible for breaking down fibrin clots. In rats, as in humans, plasminogen is primarily produced in the liver and circulates in the bloodstream, where it plays a key role in maintaining hemostatic balance. Upon activation by tissue-type or urokinase-type plasminogen activators, plasminogen is converted into plasmin, which facilitates clot degradation, tissue remodeling, and wound healing. Its involvement in inflammation and extracellular matrix remodeling also makes it a valuable biomarker for studying proteolytic activity in various physiological and pathological processes.

A rat plasminogen ELISA allows precise quantification of plasminogen levels in plasma, serum, or other biological samples. In research settings, it is widely used to investigate fibrinolysis, thrombosis, and inflammatory pathways, as well as to study tissue remodeling, wound healing, and disease models such as cardiovascular disorders, liver injury, or cancer metastasis. By providing reliable measurements of plasminogen concentrations, ELISAs enable scientists to explore the functional impact of genetic modifications, pharmacological interventions, or environmental factors on the fibrinolytic system.

Although primarily a research tool in rats, insights gained from plasminogen ELISA studies can have translational value for clinical applications. Understanding changes in plasminogen levels and activity can inform therapeutic strategies targeting clot formation, fibrinolysis, or tissue repair. Additionally, it can help model human disorders associated with plasminogen deficiency or dysregulated fibrinolysis, providing a foundation for preclinical testing of new drugs or treatment approaches before moving into human clinical studies.

This product is manufactured in USA by Eagle Biosciences.