Lactoferrin ELISA Kit

Lactoferrin is an iron-binding glycoprotein found in various secretions such as milk, saliva, tears, and mucosal fluids, as well as in the secondary granules of neutrophils. It plays a crucial role in the innate immune system by sequestering free iron, which limits bacterial growth, and by exhibiting direct antimicrobial, antiviral, and anti-inflammatory activities. Lactoferrin also modulates immune responses, promotes tissue repair, and has been implicated in regulating gut microbiota and maintaining mucosal integrity. Its multifunctional role in host defense and inflammation makes it a valuable biomarker for both physiological and pathological conditions.

The lactoferrin ELISA allows for the quantitative measurement of lactoferrin levels in various biological fluids, providing insights into neutrophil activity and inflammatory processes. In research settings, this assay is commonly used to study mucosal immunity, gastrointestinal disorders, and systemic inflammation, as well as to evaluate lactoferrin’s role in infectious diseases and cancer progression. Researchers also use lactoferrin ELISAs to investigate nutritional supplementation effects, particularly in infants and immunocompromised individuals, due to its role in iron metabolism and immune modulation.

In clinical applications, lactoferrin measurement is often employed as a non-invasive marker of inflammation, especially in the gastrointestinal tract. Elevated fecal lactoferrin, for example, can indicate active inflammatory bowel disease, distinguishing it from non-inflammatory conditions like irritable bowel syndrome. Additionally, plasma or serum lactoferrin levels may be assessed to monitor neutrophil activation in infections, sepsis, or chronic inflammatory diseases. The lactoferrin ELISA thus serves as a versatile tool for both diagnostic evaluation and monitoring therapeutic responses.

This product is manufactured in USA by Eagle Biosciences.