A2M ELISA Kit

Human Alpha-2-Macroglobulin (A2M) is a large plasma glycoprotein primarily produced by the liver, functioning as a broad-spectrum protease inhibitor. It plays a critical role in regulating proteolytic activity, immune response modulation, and cytokine transport. Because A2M binds to and inactivates a wide variety of proteases—including those released during inflammation, infection, or tissue damage—it serves as an important biomarker reflecting systemic protease activity and inflammatory status. The Human A2M ELISA Kit is designed to quantitatively measure A2M concentrations in biological samples such as serum, plasma, or cell culture supernatants, providing a reliable tool for studying physiological and pathological processes involving protease regulation.

In research settings, A2M ELISA assays are widely used to investigate inflammation, liver function, and metabolic disorders. Altered A2M levels have been associated with conditions such as liver cirrhosis, diabetes, neurodegenerative diseases, and certain cancers, making it a valuable marker in studies on disease mechanisms and biomarker discovery. In clinical and translational contexts, measuring A2M can aid in evaluating liver health, monitoring inflammation, and assessing overall proteinase–antiproteinase balance. Thus, the Human A2M ELISA Kit serves as both a research and diagnostic tool, enabling sensitive and specific quantification of A2M to support studies in immunology, metabolism, and clinical pathology.

This product is manufactured in USA by Eagle Biosciences.