Myoglobin is a heme-containing protein primarily found in skeletal and cardiac muscle, where it serves as an oxygen storage and transport molecule. In mice, as in humans, myoglobin is released into the bloodstream when muscle tissue is damaged, making it a sensitive marker of muscle injury or stress. Measuring myoglobin levels provides insight into muscle physiology, injury responses, and metabolic status in experimental models.
In research settings, mouse myoglobin is widely used to study skeletal and cardiac muscle physiology, including exercise responses, ischemia-reperfusion injury, muscular dystrophies, and drug-induced myopathies. It serves as a biomarker to assess muscle damage, repair, and regeneration in preclinical studies. Myoglobin quantification can also be used to evaluate the efficacy of therapeutic interventions targeting muscle protection or recovery.
In clinical and translational contexts, mouse myoglobin measurement is primarily used in preclinical disease models to simulate human conditions such as myocardial infarction, rhabdomyolysis, or muscular dystrophy. Elevated circulating myoglobin indicates acute muscle injury, while tissue-specific myoglobin staining helps map localized muscle damage. These assessments support the development of therapies and provide mechanistic insight into muscle-related diseases, bridging research findings to potential clinical applications.
This product is manufactured in USA by Eagle Biosciences.