Dopamine is a key neurotransmitter that plays a central role in regulating movement, motivation, reward, learning, and emotional responses. It is produced from the amino acid tyrosine through enzymatic conversion, mainly in dopaminergic neurons located in brain regions such as the substantia nigra, ventral tegmental area, and hypothalamus. Dopamine levels reflect the activity of these neural circuits and are often used as a biomarker to assess the functional state of the dopaminergic system. Its concentration can be measured in various biological samples, including brain tissue, cerebrospinal fluid, or extracellular fluid, using methods like high-performance liquid chromatography or voltammetry.
In research, dopamine is widely used to study the neurobiology of behavior and disease. Alterations in dopamine signaling are linked to disorders such as Parkinson’s disease, schizophrenia, depression, and substance use disorders. Scientists measure dopamine to examine how genetic, pharmacological, or environmental factors affect neural circuits controlling movement, cognition, and reward. Dopamine also serves as a biomarker for assessing the effectiveness of drugs that target dopaminergic pathways, helping to connect basic neuroscience findings with potential therapeutic strategies.
This product is manufactured in Germany by DLD Diagnostika.
| Size | 1 x 96 Well |
| Sensitivity | 5.9 pg/mL |
| Dynamic Range | 0.3 – 100 ng/mL |
| Incubation Time | overnight |
| Sample Type | Plasma, Cell Culture, Tissue Homogenates, Biological Fluids |
| Storage | 2-8°C |
| Alternative Names | 3,4-dihydroxyphenethylamine, DA, a catecholamine neurotransmitter, or dihydroxyphenylethylamine. |
